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Publications from the Sontheimer Lab



Preall, J. B., He, Z., Gorra, J., and Sontheimer, E. J. (2006). Short Interfering RNA Strand Selection is Independent of dsRNA Processing Polarity During RNAi in Drosophila. Curr. Biol. 16, 530-535.

Bellare, P., Kutach, A. K., Rines, A., Guthrie, C., and Sontheimer, E. J. (2006). Ubiquitin Binding by a Variant Jab1/MPN Domain in the Essential Pre-mRNA Splicing Factor Prp8p. RNA 12, 292-302.

Preall, J. B., and Sontheimer, E. J. (2005). RNAi: RISC Gets Loaded. Cell 123, 543-545.

Pham, J. W., and Sontheimer, E. J. (2005). Molecular Requirements for RISC Assembly in the Drosophila RNAi Pathway. J. Biol. Chem. 280, 39278-39283.

Pellino, J. L., Jaskiewicz, L., Filipowicz, W., and Sontheimer, E. J. (2005). A Dicer-Containing Complex Interacts with Short Interfering RNAs in Human Cell Extracts. RNA 11, 1719-1724.

Sontheimer, E. J. and Carthew, R. W. (2005). Silencing From Within: Endogenous siRNAs and miRNAs. Cell 122, 9-12.

Pham, J. W. and Sontheimer, E. J. (2005). Separation of Drosophila RNA Silencing Complexes by Native Gel Electrophoresis. In Methods in Molecular Biology, Volume 309 (G. Carmichael, Ed.). Humana Press, Totawa, New Jersey.

Sontheimer, E. J. (2005). RNA Silencing Complex Assembly and Function. Nature Reviews Molecular and Cellular Biology 6, 127-138.

Pham, J. W. and Sontheimer, E. J. (2004). The Making of an siRNA. Molecular Cell 15, 163-164.

Sontheimer, E. J. and Carthew, R. W. (2004). Argonaute Journeys Into the Heart of RISC. Science 305, 1409-1410.

He, Z., and Sontheimer, E. J. (2004). siRNAs and miRNAs: A Meeting Review on RNA Silencing. RNA 10, 1165-1173.

Pham, J. W., Radhakrishnan, I., and Sontheimer, E. J. (2004). Thermodynamic and Structural Characterization of 2'-Nitrogen-modified RNA Duplexes. Nucleic Acids Research 32, 3446-3455.

Pham, J. W., Pellino, J. L., Lee, Y. S., Carthew, R. W., and Sontheimer, E. J. (2004). A Dicer-2-Dependent 80S Complex Cleaves Targeted mRNAs during RNAi in Drosophila. Cell 117, 83-94.

Lee, Y. S., Nakahara, K., Pham, J. W., Kim, K., He, Z., Sontheimer, E. J., and Carthew, R. W. (2004). Distinct Roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA Silencing Pathways. Cell 117, 69-81.

Sontheimer, E. J. (2003). R2D2 Leads the Silencing Trigger to mRNA's Death Star. Cell 115, 132-133.

Sontheimer, E. J. (2001). The Spliceosome Shows its Metal. Nature Structural Biology 8, 11-13.

Sontheimer, E. J. (1999). Bridging Sulfur Substitution in the Analysis of Pre-mRNA Splicing. Methods 18: 29-37.






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